Article
Genetic polymorphisms of XRCC1 gene and susceptibility to hepatocellular carcinoma in Chinese population.
Medical oncology (Northwood, London, England) - 1 Apr 2014
Jiang Tao, Cui Longjiu, Chen Libo, Liu Zhongxiang, Ren Hui
Abstract excerpt
Hepatocellular carcinoma (HCC) is a common cancer in the worldwide. Accumulated evidences indicate that genetic polymorphisms of human X-ray repair complementing group 1 gene (XRCC1) are associated with the susceptibility to HCC. This study aims to investigate the potential association between XRCC1 c.482C>T and c.1178G>A genetic polymorphisms and the susceptibility to HCC. A total of 1,069 Chinese Han subjects...
Topics
- Adult
- Aged
- Asian People
- Carcinoma, Hepatocellular
- Case-Control Studies
- China
- DNA-Binding Proteins
- Female
- Genetic Predisposition to Disease
- Genotype
- Humans
- Liver Neoplasms
- Male
- Middle Aged
- Polymerase Chain Reaction
- Polymorphism, Single Nucleotide
- Sequence Analysis, DNA
- X-ray Repair Cross Complementing Protein 1