Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of type 2 deiodinase in response to acute lung injury (ALI) in mice.

Proceedings of the National Academy of Sciences of the United States of America - 6 Dec 2011

Barca-Mayo Olga, Liao Xiao-Hui, DiCosmo Caterina, Dumitrescu Alexandra, Moreno-Vinasco Liliana, Wade Michael S, Sammani Saad, Mirzapoiazova Tamara, Garcia Joe G N, Refetoff Samuel, Weiss Roy E

Abstract excerpt

Thyroid hormone (TH) metabolism, mediated by deiodinase types 1, 2, and 3 (D1, D2, and D3) is profoundly affected by acute illness. We examined the role of TH metabolism during ventilator-induced lung injury (VILI) in mice. Mice exposed to VILI recapitulated the serum TH findings of acute illness...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chemokines
Share to Acute Lung Injury

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Iodide Peroxidase

Share to Iodothyronine Deiodinase Type II

Share to Mice, 129 Strain

Share to Thyrotropin

Share to Thyroxine

Share to Triiodothyronine

Source

Open in PubMed Open full text

Identifiers

PMID: 22065740
DOI: 10.1073/pnas.1109926108
PMCID: PMC3241808

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22065740-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of type 2 deiodinase in response to acute lung injury (ALI) in mice.PMID 22065740Read ↗

Type 2 deiodinase and host responses of sepsis and acute lung injury.Semantic proximity Read ↗

Type 3 deiodinase is critical for the maturation and function of the thyroid axis.Semantic proximity Read ↗

Adult mice lacking the type 2 iodothyronine deiodinase have increased subchondral bone but normal articular cartilage.Semantic proximity Read ↗

DIO2 Thr92Ala Reduces Deiodinase-2 Activity and Serum-T3 Levels in Thyroid-Deficient Patients.Semantic proximity Read ↗

Distinct roles of deiodinases on the phenotype of Mct8 defect: a comparison of eight different mouse genotypes.Semantic proximity Read ↗

MCT8 Deficiency in Male Mice Mitigates the Phenotypic Abnormalities Associated With the Absence of a Functional Type 3 Deiodinase.Semantic proximity Read ↗

Type 2 Deiodinase Disruption in Astrocytes Results in Anxiety-Depressive-Like Behavior in Male MiceSemantic proximity Read ↗

Thyroid Hormone Deiodinases: Dynamic Switches in Developmental TransitionsSemantic proximity Read ↗

Vitamin D and the ability to produce 1,25(OH) <sub>2</sub> D are critical for protection from viral infection of the lungsSemantic proximity Read ↗

Abnormal Motor Phenotype at Adult Stages in Mice Lacking Type 2 DeiodinaseSemantic proximity Read ↗

The roles of the iodothyronine deiodinases in mammalian development.Semantic proximity Read ↗

Thyroid hormone transporters in health and disease: advances in thyroid hormone deiodination.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.