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Article

Polyploidy spectrum: a new marker in HCC classification

12 Apr 2019

Abstract excerpt

Objectives Polyploidy is a fascinating characteristic of liver parenchyma. Hepatocyte polyploidy depends on the DNA content of each nucleus (nuclear ploidy) and the number of nuclei per cell (cellular ploidy). Which role can be assigned to polyploidy during human hepatocellular carcinoma (HCC) development is still an open question. Here, we investigated whether a specific ploidy spectrum is associated with...

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Share to Genomic variations and chromosomal abnormalities
Share to Hepatocellular Carcinoma Treatment and Prognosis
Share to Microtubule and mitosis dynamics

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PMID: 30979717
DOI: 10.1136/gutjnl-2018-318021

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