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Article

Metastatic cutaneous squamous cell carcinoma shows frequent deletion in the protein tyrosine phosphatase receptor Type D gene.

International journal of cancer - 1 Aug 2012

Lambert Sally R, Harwood Catherine A, Purdie Karin J, Gulati Abha, Matin Rubeta N, Romanowska Malgorzata, Cerio Rino, Kelsell David P, Leigh Irene M, Proby Charlotte M

Abstract excerpt

Cutaneous squamous cell carcinoma (cSCC) is the second most common form of nonmelanoma skin cancer (NMSC), and its incidence is increasing rapidly. Metastatic cSCC accounts for the majority of deaths associated with NMSC, but the genetic basis for cSCC progression remains poorly understood. A previous study identified small deletions (typically <1 Mb) in the protein tyrosine phosphatase receptor Type D (PTPRD)...

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Share to Carcinoma, Squamous Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasm Metastasis

Share to Oligonucleotide Array Sequence Analysis

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Share to Receptor-Like Protein Tyrosine Phosphatases, Class 2

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Source

Identifiers

PMID: 22052591
DOI: 10.1002/ijc.27333

Genes

PTPRD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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