Article

Comprehensive molecular characterization of cutaneous squamous cell carcinoma reveals determinants of metastatic progression

2026-07-20

Abstract excerpt

Cutaneous squamous cell carcinoma (cSCC) is the second most common form of cancer worldwide. While most cSCCs are not life-threatening, 2-5% of patients develop metastases. To better understand what causes some cSCCs to progress to metastatic disease, we assembled a nationwide cohort of 19,120 patients with clinico-pathologically annotated tumors linked to metastatic outcome. RNA-sequencing was performed on 378 tu...

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Literature Corpus work: e6690d07-1ee5-56e9-ba62-493dfebdef89
DOI: 10.64898/2026.07.17.26358051

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