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Genome-Wide Methylation Profiles of Primary and Matched Distant Metastasis: Insights from the Dutch Early-Stage Melanoma (D-Esmel) Study

2025-10-08

Abstract excerpt

<title>Abstract</title> <p> Background Early-stage (stage I-II) cutaneous melanoma accounts for the majority of melanoma diagnoses, but more than 40% of patients who die due to melanoma were initially diagnosed with an early-stage melanoma. Methods The aim of this study was to identify prognostic genome-wide methylation markers of metastasized primary early-stage melanomas and retrieving biological insights from...

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Literature Corpus work: cf5f6d9a-29f4-5c62-b741-deb82286040e
DOI: 10.21203/rs.3.rs-7642695/v1

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