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Article

MTHFR polymorphisms, folate intake and carcinogen DNA adducts in the lung.

International journal of cancer - 1 Sept 2012

Lee Mi-Sun, Asomaning Kofi, Su Li, Wain John C, Mark Eugene J, Christiani David C

Abstract excerpt

The methylenetetrahydrofolate reductase (MTHFR) genes and folate in one-carbon metabolism are essential for DNA methylation and synthesis. However, their role in carcinogen DNA damage in target lung tissue, a dosimeter for cancer risk, is not known. Our study aimed to investigate the association between genetic and nutritional one-carbon metabolism factors and DNA adducts in target lung. Data on 135 lung cancer...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Methylenetetrahydrofolate Reductase (NADPH2)

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Source

Open in PubMed Open full text

Identifiers

PMID: 22052259
DOI: 10.1002/ijc.27338
PMCID: PMC3293105

Genes

MTHFR

Variants

rs1801133
rs1801133

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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