Article
Folate-related genes and the risk of tobacco-related cancers in Central Europe.
Carcinogenesis - 1 Jun 2007
Hung Rayjean J, Hashibe Mia, McKay James, Gaborieau Valerie, Szeszenia-Dabrowska Neonila, Zaridze David, Lissowska Jolanta, Rudnai Peter, Fabianova Eleonora, Mates Ioan, Foretova Lenka, Janout Vladimir, Bencko Vladimir, Chabrier Amelie, Moullan Norman, Canzian Federico, Hall Janet, Boffetta Paolo, Brennan Paul
Abstract excerpt
Folate has been hypothesized to protect against aero-digestive cancers although the evidence is not yet conclusive due to possible confounding by other dietary factors. Sequence variants in folate pathway were suggested to be associated with plasma folate levels and are unlikely to be confounded by other lifestyle factors. We therefore investigated the effects of key folate genetic variants on the risk of...
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