Article
Evolutionary variation of the CCAAT-binding transcription factor NF-Y.
Nucleic acids research - 11 Mar 1992
Li X Y, Mantovani R, Hooft van Huijsduijnen R, Andre I, Benoist C, Mathis D
Abstract excerpt
NF-Y is a CCAAT-specific transcription factor thought to be involved in the regulation of a variety of eukaryotic genes. It shows a striking sequence similarity with the yeast factor HAP2/3. In an attempt to trace back its evolutionary history, we succeeded in isolating NF-Y cDNA clones from a plant and from several species of vertebrates. The patterns of sequence conservation delineate potential functional...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Biological Evolution
- CCAAT-Enhancer-Binding Proteins
- DNA-Binding Proteins
- Fungi
- Genetic Variation
- Humans
- Molecular Sequence Data
- Polymerase Chain Reaction