Article
Dominant negative analogs of NF-YA.
The Journal of biological chemistry - 12 Aug 1994
Mantovani R, Li X Y, Pessara U, Hooft van Huisjduijnen R, Benoist C, Mathis D
Abstract excerpt
NF-Y is a highly conserved heteromeric CCAAT-binding transcription factor involved in the function of several promoters. The NF-YA subunit contains a domain of high homology to yeast HAP2, which we show to be necessary and sufficient to mediate interactions with the NF-YB subunit and with DNA. Us...
Topics
- Amino Acid Sequence
- Base Sequence
- CCAAT-Enhancer-Binding Proteins
- DNA
- DNA-Binding Proteins
- Genes, Dominant
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- Oligodeoxyribonucleotides
- Sequence Alignment
- Structure-Activity Relationship
- Transcription Factors