Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dominant negative analogs of NF-YA.

The Journal of biological chemistry - 12 Aug 1994

Mantovani R, Li X Y, Pessara U, Hooft van Huisjduijnen R, Benoist C, Mathis D

Abstract excerpt

NF-Y is a highly conserved heteromeric CCAAT-binding transcription factor involved in the function of several promoters. The NF-YA subunit contains a domain of high homology to yeast HAP2, which we show to be necessary and sufficient to mediate interactions with the NF-YB subunit and with DNA. Using protein affinity columns derivatized with amino acid substitution mutants, we further dissect this region into two...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA
Share to DNA-Binding Proteins
Share to Molecular Sequence Data

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to Nuclear Proteins

Share to Transcription Factors

Share to Amino Acid Sequence

Share to Base Sequence

Source

Identifiers

PMID: 8051128

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dominant negative analogs of NF-YA.PMID 8051128Read ↗

Evolutionary variation of the CCAAT-binding transcription factor NF-Y.Semantic proximity Read ↗

NF-Y binding to twin CCAAT boxes: role of Q-rich domains and histone fold helices.Semantic proximity Read ↗

NF-Y and the transcriptional activation of CCAAT promoters.Semantic proximity Read ↗

Dissection of the NF-Y transcriptional activation potential.Semantic proximity Read ↗

Three classes of mutations in the A subunit of the CCAAT-binding factor CBF delineate functional domains involved in the three-step assembly of the CBF-DNA complex.Semantic proximity Read ↗

The CCAAT-binding complex of eukaryotes: evolution of a second NLS in the HapB subunit of the filamentous fungus Aspergillus nidulans despite functional conservation at the molecular level between yeast, A.nidulans and human.Semantic proximity Read ↗

Functional and transcriptome analysis reveals an acclimatization strategy for abiotic stress tolerance mediated by Arabidopsis NF-YA family members.Semantic proximity Read ↗

The NF-Y complex negatively regulates Caenorhabditis elegans tbx-2 expression.Semantic proximity Read ↗

The Nuclear Factor Y subunits NF-YB2 and NF-YB3 play additive roles in the promotion of flowering by inductive long-day photoperiods in Arabidopsis.Semantic proximity Read ↗

Transcriptional activators HAP/NF-Y rescue a cytochrome c oxidase defect in yeast and human cells.Semantic proximity Read ↗

Diversification of Transcription Factor NF-κB in ProtistsSemantic proximity Read ↗

YEAF1/RYBP and YAF-2 are functionally distinct members of a cofactor family for the YY1 and E4TF1/hGABP transcription factors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.