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Article

Dopamine effects on human error processing depend on catechol-O-methyltransferase VAL158MET genotype.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 2 Nov 2011

Mueller Erik M, Makeig Scott, Stemmler Gerhard, Hennig Jürgen, Wacker Jan

Abstract excerpt

Brain dopamine (DA) has been linked to error processing. Because high and low (vs medium) prefrontal cortex (PFC) DA levels may facilitate D2-receptor-related modulations of PFC neural activation patterns, we hypothesized that high and low DA predicts increased error-specific transitions of PFC activity. Male human participants (n = 169) were genotyped for the catechol-O-methyltransferase (COMT) Val158Met...

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Identifiers

PMID: 22049425
DOI: 10.1523/JNEUROSCI.2103-11.2011
PMCID: PMC6623004

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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