Article
Rapid determination of common mutations in glutathione S-transferase gene by PCR-based methods in healthy Chinese.
Clinica chimica acta; international journal of clinical chemistry - 1 Feb 2006
Zhong Shi-long, Zhou Shufeng, Chen Xiao, Huang Min
Abstract excerpt
BACKGROUND: The glutathione S-transferase (GST) superfamily comprises multiple isozymes with compelling evidence of functional polymorphisms in various ethnic groups. All these mutations, in particular those in class mu, pi and theta GST, are likely to contribute to interindividual differences in responses to xenobiotics including response to chemotherapy and associated with altered disease. The frequency of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.