Article
Glutathione S transferase theta1 and mu1 gene polymorphisms and phenotypic expression of asthma in Egyptian children: a case-control study.
Italian journal of pediatrics - 21 Feb 2014
El Rifai Nihal, Moustafa Nadia, Degheidy Nelly, Wilson Manal
Abstract excerpt
BACKGROUND: Asthma is the result of a complex interaction between environmental factors and genetic variants that confer susceptibility. The glutathione S-transferases (GSTT1 and GSTM1) are phase II enzymes thought to protect the airways from oxidative stress. Few and contradictory data are available on the association between asthma development and GSTT1 and GSTM1 polymorphisms in different ethnic groups. The...
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