Article
A novel immunodominant CD8+ T cell response restricted by a common HLA-C allele targets a conserved region of Gag HIV-1 clade CRF01_AE infected Thais.
PloS one - 1 Jan 2011
Buranapraditkun Supranee, Hempel Ursula, Pitakpolrat Patrawadee, Allgaier Rachel L, Thantivorasit Pattarawat, Lorenzen Sven-Iver, Sirivichayakul Sunee, Hildebrand William H, Altfeld Marcus, Brander Christian, Walker Bruce D, Phanuphak Praphan, Hansasuta Pokrath, Rowland-Jones Sarah L, Allen Todd M, Ruxrungtham Kiat
Abstract excerpt
BACKGROUND: CD8+ T cell responses play an important role in the control of HIV-1. The extensive sequence diversity of HIV-1 represents a critical hurdle to developing an effective HIV-1 vaccine, and it is likely that regional-specific vaccine strains will be required to overcome the diversity of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
