Article
Copy number variations of interleukin-17F, interleukin-21, and interleukin-22 are associated with systemic lupus erythematosus.
Arthritis and rheumatism - 1 Nov 2011
Yu Bo, Guan Ming, Peng Yinghui, Shao Yong, Zhang Chao, Yue Xupeng, Zhang Jie, Yang Hong, Zou Hejian, Ye Wencai, Wan Jun, Zhang Wei
Abstract excerpt
OBJECTIVE: Systemic lupus erythematosus (SLE) represents the classic prototype of systemic autoimmune disease. The identification of the Th17 cell subset has provided new understanding regarding the underlying mechanisms of autoimmunity. Copy number variations (CNVS) have been discovered to have phenotypic consequences and are associated with various types of diseases. We undertook this study to explore a...
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