Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of IL10RA, IL10RB, and IL22RA Polymorphisms/Haplotypes with Susceptibility to and Clinical Manifestations of SLE.

International journal of molecular sciences - 10 Jul 2023

Grk Milka, Miskovic Rada, Jeremic Ivica, Basaric Milica, Dusanovic Pjevic Marija, Jekic Biljana, Miljanovic Danijela, Lazarevic Ivana, Despotovic Aleksa, Cirkovic Andja, Banko Ana

Abstract excerpt

Systemic lupus erythematosus (SLE) is characterized by an imbalance between proinflammatory and anti-inflammatory mediators. Single-nucleotide polymorphisms (SNPs) in genes coding IL10RA, IL10RB, and IL22RA could affect their expression or function and disrupt immune homeostasis. We aimed to analyze the associations of IL10RA, IL10RB, and IL22RA polymorphisms/haplotypes with patients' susceptibility to and...

Topics

Join the communities discussing this publication.

Case-Control Studies
Gene Frequency
Genetic Predisposition to Disease
Genotype
Haplotypes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hashimoto Disease

Lupus Erythematosus, Systemic

Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 37511050
DOI: 10.3390/ijms241411292
PMCID: PMC10379357

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of IL10RA, IL10RB, and IL22RA Polymorphisms/Haplotypes with Susceptibility to and Clinical Manifestations of SLE.PMID 37511050Read ↗

IL-10RB rs2834167 (A/G) polymorphism is associated with the susceptibility to systemic lupus erythematosus: evidence from a study in Chinese Han population.Semantic proximity Read ↗

Association of interleukin-10 gene single nucleotide polymorphisms with susceptibility to systemic lupus erythematosus in a Chinese population.Semantic proximity Read ↗

Association of interleukin 22 gene polymorphisms and serum IL-22 level with risk of systemic lupus erythematosus in a Chinese population.Semantic proximity Read ↗

Plasma interleukin-22 level, variants in interleukin-22 gene polymorphism, and the severity of systemic lupus erythematosus among Egyptian pediatric and adolescents.Semantic proximity Read ↗

IL-1β, IL-10 and TNF-α polymorphisms may affect systemic lupus erythematosus risk and phenotype.Semantic proximity Read ↗

Interleukin10 gene promoter polymorphisms (rs1800896, rs1800871 and rs1800872) and haplotypes are associated with the activity of systemic lupus erythematosus and IL10 levels in an Iranian populationSemantic proximity Read ↗

The role of IL-17 rs2275913, IL-17RC rs708567 and TGFB1 rs1800469 SNPs and IL-17A serum levels in patients with lupus nephritis.Semantic proximity Read ↗

IL-10 gene polymorphisms and susceptibility to systemic lupus erythematosus: a meta-analysis.Semantic proximity Read ↗

Interleukin-10 gene polymorphisms are associated with the SLICC/ACR Damage Index in systemic lupus erythematosus.Semantic proximity Read ↗

Associations between interleukin-10 polymorphisms and susceptibility to systemic lupus erythematosus: a meta-analysis.Semantic proximity Read ↗

Association of CD40 polymorphisms and haplotype with risk of systemic lupus erythematosus.Semantic proximity Read ↗

Impact of the IL-17F, IL-23 and IL-23R on susceptibility and phenotype of systemic lupus erythematosus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.