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Article

Copy number variations of Interleukin-12B and T-bet are associated with systemic lupus erythematosus.

Rheumatology (Oxford, England) - 1 Jul 2011

Yu Bo, Shao Yong, Yue Xupeng, Zhang Jie, Guan Ming, Wan Jun, Zhang Wei

Abstract excerpt

OBJECTIVES: Th1 cells have been implicated as the causal agents in the pathogenesis of autoimmunity. SLE represents the classical prototype of systemic autoimmune disease. Copy number variations (CNVs) have been discovered to have phenotypic consequences and associate with various types of diseases. The current study aims to explore a possible association between CNVs of Th1 cell-related genes and the risk of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21278068
DOI: 10.1093/rheumatology/keq439

Genes

CXCR3
GATA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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