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Article

IL-17A, IL-23R, FCGR3A are associated with neuropsychiatric systemic lupus erythematosus susceptibility in pediatric patients with lupus nephritis.

Cytokine - 1 Apr 2025

Ye Chen, Chen Lizhi, Zhang Lu, Zheng Yifan, Liu Xiaohong, Huang Zhijun, Tang Kejing, Jiang Xiaoyun, Chen Pan

Abstract excerpt

OBJECTIVE: To comprehensively investigate the impact of candidate loci on the susceptibility to neuropsychiatric systemic lupus erythematosus (NPSLE) in a cohort of Chinese children with lupus nephritis (LN). METHODS: This case-control study included sixty-two patients. And the case group consisted of 12 LN patients appearing NPSLE, while the control group consisted of 50 LN patients. A total of fifty-four single...

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Identifiers

PMID: 39904110
DOI: 10.1016/j.cyto.2025.156874

Genes

FCGR3A
IL17RA
IL23R
STAT4

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