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Article

PPARα is down-regulated following liver transplantation in mice.

Journal of hepatology - 1 Mar 2012

Nakagawa Kan, Tanaka Naoki, Morita Miwa, Sugioka Atsushi, Miyagawa Shin-ichi, Gonzalez Frank J, Aoyama Toshifumi

Abstract excerpt

BACKGROUND & AIMS: Graft dysfunction is one of the major complications after liver transplantation, but its precise mechanism remains unclear. Since steatotic liver grafts are susceptible to post-transplant dysfunction, and peroxisome proliferator-activated receptor (PPAR) α plays an important role in the maintenance of hepatic lipid homeostasis, we examined the role of PPARα in liver transplantation. METHODS:...

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Identifiers

PMID: 22037025
DOI: 10.1016/j.jhep.2011.08.021
PMCID: PMC6399745

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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