Article
Peroxisome proliferator-activated receptor beta/delta exerts a strong protection from ischemic acute renal failure.
Journal of the American Society of Nephrology : JASN - 1 Aug 2005
Letavernier Emmanuel, Perez Joëlle, Joye Elisabeth, Bellocq Agnès, Fouqueray Bruno, Haymann Jean-Philippe, Heudes Didier, Wahli Walter, Desvergne Béatrice, Baud Laurent
Abstract excerpt
Ischemic acute renal failure is characterized by damages to the proximal straight tubule in the outer medulla. Lesions include loss of polarity, shedding into the tubule lumen, and eventually necrotic or apoptotic death of epithelial cells. It was recently shown that peroxisome proliferator-activ...
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