Article
Donor PPARα Gene Polymorphisms Influence the Susceptibility to Glucose and Lipid Disorders in Liver Transplant Recipients: A Strobe-Compliant Observational Study.
Medicine - 1 Sept 2015
Ling Qi, Xu Xiao, Wang Kai, Wang Chao, Xiang Penghui, Zhang Xuanyu, Zhuang Runzhou, Xie Haiyang, Zheng Shusen
Abstract excerpt
Peroxisome proliferator-activated receptor α (PPARα) is an important regulator of glucose and lipid metabolism, and is predominantly expressed in the liver. We aimed to evaluate the effect of donor hepatic PPARα gene polymorphisms on the development of metabolic disorders following liver transplantation (LT).A total of 176 patients undergoing primary LT were included in this Review Board-approved study. Genomic...
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