Article
Radiographic severity of ankylosing spondylitis is associated with polymorphism of the large multifunctional peptidase 2 gene in the Spondyloarthritis Research Consortium of Canada cohort.
Arthritis and rheumatism - 1 Apr 2012
Haroon Nigil, Maksymowych Walter P, Rahman Proton, Tsui Florence W L, O'Shea Finbar D, Inman Robert D
Abstract excerpt
OBJECTIVE: There are limited data on genetic predictors of radiographic progression. The aim of this study was to examine polymorphisms in genes involved in antigen presentation and their effect on radiographic severity and progression. METHODS: Caucasian patients with ankylosing spondylitis (AS) (diagnosed according to the modified New York criteria) from 2 Canadian centers were enrolled. Patients in the...
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