Article
Association study of genes related to bone formation and resorption and the extent of radiographic change in ankylosing spondylitis.
Annals of the rheumatic diseases - 1 Jul 2015
Cortes A, Maksymowych W P, Wordsworth B P, Inman R D, Danoy P, Rahman P, Stone M A, Corr M, Gensler Lianne S, Gladman D, Morgan A, Marzo-Ortega H, Ward M M, Learch T J, Reveille J D, Brown M A, Weisman M H
Abstract excerpt
OBJECTIVE: To identify genetic associations with severity of radiographic damage in ankylosing spondylitis (AS). METHOD: We studied 1537 AS cases of European descent; all fulfilled the modified New York Criteria. Radiographic severity was assessed from digitised lateral radiographs of the cervical and lumbar spine using the modified Stoke Ankylosing Spondylitis Spinal Score (mSASSS). A two-phase genotyping design...
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