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Article

Association of a specific ERAP1/ARTS1 haplotype with disease susceptibility in ankylosing spondylitis.

Arthritis and rheumatism - 1 May 2009

Maksymowych W P, Inman R D, Gladman D D, Reeve J P, Pope A, Rahman P

Abstract excerpt

OBJECTIVE: Alterations in antigen processing have been proposed to play a significant role in the pathogenesis of ankylosing spondylitis (AS). A non-major histocompatibility complex gene encoding an endoplasmic reticulum aminopeptidase, ERAP1, has been implicated recently. This study assessed 13 coding single-nucleotide polymorphisms (SNPs) from 5 genes involved in antigen processing (ERAP1, TAP1, TAP2, LMP2, and...

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Share to Aminopeptidases
Share to ATP Binding Cassette Transporter, Subfamily B, Member 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19404951
DOI: 10.1002/art.24467

Genes

ERAP1
TAP1
TAP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of a specific ERAP1/ARTS1 haplotype with disease susceptibility in ankylosing spondylitis.PMID 19404951Read ↗

ERAP1 in the pathogenesis of ankylosing spondylitis.Semantic proximity Read ↗

Associations between ERAP1 polymorphisms and ankylosing spondylitis susceptibility: a meta-analysis.Semantic proximity Read ↗

ERAP1 is associated with ankylosing spondylitis in Han Chinese.Semantic proximity Read ↗

A polymorphism in ERAP1 is associated with susceptibility to ankylosing spondylitis in a Turkish population.Semantic proximity Read ↗

Association of an ERAP1 ERAP2 haplotype with familial ankylosing spondylitis.Semantic proximity Read ↗

Associations between ERAP1 polymorphisms and ankylosing spondylitis susceptibility: An updated meta-analysis.Semantic proximity Read ↗

ERAP1 polymorphisms and haplotypes are associated with ankylosing spondylitis susceptibility and functional severity in a Spanish population.Semantic proximity Read ↗

Associations between ERAP1 polymorphisms and susceptibility to ankylosing spondylitis: a meta-analysis.Semantic proximity Read ↗

The association between seven ERAP1 polymorphisms and ankylosing spondylitis susceptibility: a meta-analysis involving 8,530 cases and 12,449 controls.Semantic proximity Read ↗

Functionally distinct ERAP1 allotype combinations distinguish individuals with Ankylosing Spondylitis.Semantic proximity Read ↗

Investigating the genetic association between ERAP1 and spondyloarthritis.Semantic proximity Read ↗

The influence of ERAP1 gene variants on clinical phenotype in ankylosing spondylitis.Semantic proximity Read ↗

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