Article
Is disease severity in ankylosing spondylitis genetically determined?
Arthritis and rheumatism - 1 Jun 2001
Hamersma J, Cardon L R, Bradbury L, Brophy S, van der Horst-Bruinsma I, Calin A, Brown M A
Abstract excerpt
OBJECTIVE: To assess the role of genes and the environment in determining the severity of ankylosing spondylitis. METHODS: One hundred seventy-three families with >1 case of ankylosing spondylitis were recruited (120 affected sibling pairs, 26 affected parent-child pairs, 20 families with both first- and second-degree relatives affected, and 7 families with only second-degree relatives affected), comprising a...
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