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Characterization, Mapping, and Distribution of the Two XMRV Parental Proviruses

27 Oct 2011

Abstract excerpt

Xenotropic murine leukemia virus-related virus (XMRV) was previously reported to be associated with human prostate cancer and chronic fatigue syndrome. Our groups recently showed that XMRV was created through recombination between two endogenous murine retroviruses, PreXMRV-1 and PreXMRV-2, during the passaging of a prostate tumor xenograft in nude mice. Here, multiple approaches that led to the identification of...

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Identifiers

PMID: 22031947
DOI: 10.1128/jvi.06022-11

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