Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multiple Integrated Copies and High-Level Production of the Human Retrovirus XMRV (Xenotropic Murine Leukemia Virus-Related Virus) from 22Rv1 Prostate Carcinoma Cells

29 Apr 2009

Abstract excerpt

The human retrovirus XMRV (xenotropic murine leukemia virus-related virus) is associated with prostate cancer, most frequently in humans with a defect in the antiviral defense protein RNase L, suggesting a role for XMRV in prostate carcinogenesis. However, XMRV has not been found in prostate carcinoma cells. Here we show that 22Rv1 prostate carcinoma cells produce high-titer virus that is nearly identical in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hepatitis B Virus Studies
Share to Immunotherapy and Immune Responses
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19403664
DOI: 10.1128/jvi.00546-09

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multiple Integrated Copies and High-Level Production of the Human Retrovirus XMRV (Xenotropic Murine Leukemia Virus-Related Virus) from 22Rv1 Prostate Carcinoma CellsPMID 19403664Read ↗

Biology and pathophysiology of the new human retrovirus XMRV and its association with human disease.Semantic proximity Read ↗

Absence of XMRV and closely related viruses in primary prostate cancer tissues used to derive the XMRV-infected cell line 22Rv1.Semantic proximity Read ↗

Identification of Replication Competent Murine Gammaretroviruses in Commonly Used Prostate Cancer Cell LinesSemantic proximity Read ↗

XMRV is present in malignant prostatic epithelium and is associated with prostate cancer, especially high-grade tumors.Semantic proximity Read ↗

In-depth investigation of archival and prospectively collected samples reveals no evidence for XMRV infection in prostate cancer.Semantic proximity Read ↗

Contamination of clinical specimens with MLV-encoding nucleic acids: implications for XMRV and other candidate human retrovirusesSemantic proximity Read ↗

The Prostate Cancer-Associated Human Retrovirus XMRV Lacks Direct Transforming Activity but Can Induce Low Rates of Transformation in Cultured CellsSemantic proximity Read ↗

Recombinant Origin of the Retrovirus XMRVSemantic proximity Read ↗

Characterization, Mapping, and Distribution of the Two XMRV Parental ProvirusesSemantic proximity Read ↗

Detection of xenotropic murine leukemia virus-related virus in normal and tumor tissue of patients from the southern United States with prostate cancer is dependent on specific polymerase chain reaction conditions.Semantic proximity Read ↗

Fibrils of Prostatic Acid Phosphatase Fragments Boost Infections with XMRV (Xenotropic Murine Leukemia Virus-Related Virus), a Human Retrovirus Associated with Prostate CancerSemantic proximity Read ↗

No association of xenotropic murine leukemia virus-related viruses with prostate cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.