Article
Endogenous gammaretrovirus acquisition in Mus musculus subspecies carrying functional variants of the XPR1 virus receptor.
Journal of virology - 1 Sept 2013
Bamunusinghe Devinka, Liu Qingping, Lu Xiaoyu, Oler Andrew, Kozak Christine A
Abstract excerpt
The xenotropic and polytropic mouse leukemia viruses (X-MLVs and P-MLVs, respectively) have different host ranges but use the same functionally polymorphic receptor, XPR1, for entry. Endogenous retroviruses (ERVs) of these 2 gammaretrovirus subtypes are largely segregated in different house mouse subspecies, but both MLV types are found in the classical strains of laboratory mice, which are genetic mosaics of 3...
Topics
- Alleles
- Animals
- Animals, Wild
- Endogenous Retroviruses
- Evolution, Molecular
- Genetic Variation
- Host Specificity
- Leukemia Virus, Murine
- Mice
- Mice, Inbred C57BL
- Mice, Inbred Strains
