Article
Evolution of functional and sequence variants of the mammalian XPR1 receptor for mouse xenotropic gammaretroviruses and the human-derived retrovirus XMRV.
Journal of virology - 1 Nov 2010
Yan Yuhe, Liu Qingping, Wollenberg Kurt, Martin Carrie, Buckler-White Alicia, Kozak Christine A
Abstract excerpt
Genetic conflicts between retroviruses and their receptors result in the evolution of novel host entry restrictions and novel virus envelopes, and such variants can influence trans-species transmission. We screened rodents and other mammals for sequence variation in the Xpr1 receptor for the mouse xenotropic or polytropic mouse leukemia viruses (X-MLVs or P-MLVs, respectively) of the gammaretrovirus family and...
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