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The mouse "xenotropic" gammaretroviruses and their XPR1 receptor

30 Nov 2010

Abstract excerpt

The xenotropic/polytropic subgroup of mouse leukemia viruses (MLVs) all rely on the XPR1 receptor for entry, but these viruses vary in tropism, distribution among wild and laboratory mice, pathogenicity, strategies used for transmission, and sensitivity to host restriction factors. Most, but not all, isolates have typical xenotropic or polytropic host range, and these two MLV tropism types have now been detected...

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PMID: 21118532
DOI: 10.1186/1742-4690-7-101

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