Signal peptide mutants of Escherichia coli.

Abstract excerpt

Numerous secretory proteins of the Gram-negative bacteria E. coli are synthesized as precursor proteins which require an amino terminal extension known as the signal peptide for translocation across the cytoplasmic membrane. Following translocation, the signal peptide is proteolytically cleaved from the precursor to produce the mature exported protein. Signal peptides do not exhibit sequence homology, but...

Topics

• Amino Acid Sequence
• Bacterial Proteins
• Escherichia coli
• Molecular Sequence Data
• Mutation
• Protein Sorting Signals