Article
Mapping of catalytically important domains in Escherichia coli leader peptidase.
The EMBO journal - 1 Sept 1990
Bilgin N, Lee J I, Zhu H Y, Dalbey R, von Heijne G
Abstract excerpt
Leader peptidase (Lep) is a central component of the secretory machinery of Escherichia coli, where it serves to remove signal peptides from secretory proteins. It spans the inner membrane twice with a large C-terminal domain protruding into the periplasmic space. To investigate the importance of...
Topics
- Amino Acid Sequence
- Bacterial Outer Membrane Proteins
- Capsid
- Cell Membrane
- Coliphages
- Cytoplasm
- Endopeptidases
- Escherichia coli
- Kinetics
- Membrane Proteins
- Molecular Sequence Data
- Mutation
- Protein Conformation
- Protein Processing, Post-Translational
- Serine Endopeptidases