Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Essential role of tryptophan residues in toxicity of binary toxin from Bacillus sphaericus.

BMB reports - 1 Oct 2011

Kunthic Thittaya, Promdonkoy Boonhiang, Srikhirin Toemsak, Boonserm Panadda

Abstract excerpt

Bacillus sphaericus produces mosquito-larvicidal binary toxin composed of BinA and BinB. While BinB is expected to bind to a specific receptor on the cell membrane, BinA interacts to BinB or BinB receptor complex and translocates into the cytosol to exert its activity via unknown mechanism. To investigate functional roles of aromatic cluster in BinA, amino acids at positions Y213, Y214, Y215, W222 and W226 were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacillus
Share to Bacterial Toxins
Share to Culex

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Insecticides

Share to Mutation

Share to Protein Folding

Share to Tryptophan

Source

Identifiers

PMID: 22027002
DOI: 10.5483/BMBRep.2011.44.10.674

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Essential role of tryptophan residues in toxicity of binary toxin from Bacillus sphaericus.PMID 22027002Read ↗

Targeted mutagenesis at charged residues in Bacillus sphaericus BinA toxin affects mosquito-larvicidal activity.Semantic proximity Read ↗

Identification of the functional site in the mosquito larvicidal binary toxin of Bacillus sphaericus 1593M by site-directed mutagenesis.Semantic proximity Read ↗

Essential role of amino acids in αD-β4 loop of a Bacillus thuringiensis Cyt2Aa2 toxin in binding and complex formation on lipid membrane.Semantic proximity Read ↗

Functional complementation of nontoxic mutant binary toxins of Bacillus sphaericus 1593M generated by site-directed mutagenesis.Semantic proximity Read ↗

The N-terminal third of the BinB subunit from the Bacillus sphaericus binary toxin is sufficient for its interaction with midgut receptors in Culex quinquefasciatus.Semantic proximity Read ↗

Molecular requirements for the insecticidal activity of the plant peptide pea albumin 1 subunit b (PA1b).Semantic proximity Read ↗

Binding of purified Bacillus sphaericus binary toxin and its deletion derivatives to Culex quinquefasciatus gut: elucidation of functional binding domains.Semantic proximity Read ↗

Identification and characterization of the receptor for the Bacillus sphaericus binary toxin in the malaria vector mosquito, Anopheles gambiaeSemantic proximity Read ↗

N546 in beta18-beta19 loop is important for binding and toxicity of the Bacillus thuringiensis Cry1Ac toxin.Semantic proximity Read ↗

Highly Effective Broad Spectrum Chimeric Larvicide That Targets Vector Mosquitoes Using a Lipophilic ProteinSemantic proximity Read ↗

Functional Study of Haemophilus ducreyi Cytolethal Distending Toxin Subunit B.Semantic proximity Read ↗

Variants of the Bacillus sphaericus binary toxins: implications for differential toxicity of strains.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.