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Article

N546 in beta18-beta19 loop is important for binding and toxicity of the Bacillus thuringiensis Cry1Ac toxin.

Journal of invertebrate pathology - 1 Jun 2009

Xiang Wang Fa, Qiu Xia Li, Zhi Ding Xue, Min Zhao Xin, Yuan Lv, Quan Yu Zi

Abstract excerpt

Our previous mutagenic analysis showed that the unique residue N546 in the apex of beta18-beta19 loop of Bacillus thuringiensis Cry1Ac toxin is important for its toxicity. In this study, trypsin digestion susceptibility, binding to BBMV and oligomer formation activity was therefore analyzed to determine the mechanism of toxicity change of these mutant toxins. The results showed that residue N546 was not involved...

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Identifiers

PMID: 19416731
DOI: 10.1016/j.jip.2009.04.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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