Article
Characterization of a Mycobacterium smegmatis uvrA mutant impaired in dormancy induced by hypoxia and low carbon concentration.
BMC microbiology - 18 Oct 2011
Cordone Angela, Audrain Bianca, Calabrese Immacolata, Euphrasie Daniel, Reyrat Jean-Marc
Abstract excerpt
BACKGROUND: The aerobic fast-growing Mycobacterium smegmatis, like its slow-growing pathogenic counterpart Mycobacterium tuberculosis, has the ability to adapt to microaerobiosis by shifting from growth to a non-proliferating or dormant state. The molecular mechanism of dormancy is not fully understood and various hypotheses have been formulated to explain it. In this work, we open new insight in the knowledge of...
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