How <i>Mycobacterium Tuberculosis</i> goes to Sleep: The Dormancy Survival Regulator DosR a Decade Later

Abstract excerpt

With 2 million deaths per year, TB remains the most significant bacterial killer. The long duration of chemotherapy and the large pool of latently infected people represent challenges in disease control. To develop drugs that effectively eradicate latent infection and shorten treatment duration, the pathophysiology of the causative agent Mycobacterium tuberculosis needs to be understood. The discovery that the...

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