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Article

Mycobacterium bovis BCG response regulator essential for hypoxic dormancy.

Journal of bacteriology - 1 Dec 2002

Boon Calvin, Dick Thomas

Abstract excerpt

Obligately aerobic tubercle bacilli are capable of adapting to survive hypoxia by developing into a nonreplicating or dormant form. Dormant bacilli maintain viability for extended periods. Furthermore, they are resistant to antimycobacterials, and hence, dormancy might play a role in the persistence of tuberculosis infection despite prolonged chemotherapy. Previously, we have grown dormant Mycobacterium bovis BCG...

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Identifiers

PMID: 12446625
DOI: 10.1128/JB.184.24.6760-6767.2002
PMCID: PMC135468

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Source receipt: pubmed, retrieved 7 Sept 2026.

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