Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Important role of the nucleotide excision repair pathway in Mycobacterium smegmatis in conferring protection against commonly encountered DNA-damaging agents.

Microbiology (Reading, England) - 1 Sept 2008

Kurthkoti Krishna, Kumar Pradeep, Jain Ruchi, Varshney Umesh

Abstract excerpt

Mycobacteria are an important group of human pathogens. Although the DNA repair mechanisms in mycobacteria are not well understood, these are vital for the pathogen's persistence in the host macrophages. In this study, we generated a null mutation in the uvrB gene of Mycobacterium smegmatis to allow us to compare the significance of the nucleotide excision repair (NER) pathway with two important base excision...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anaerobiosis
Share to DNA Damage

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA-Formamidopyrimidine Glycosylase

Share to Endodeoxyribonucleases

Share to Hydrogen Peroxide

Share to Mycobacterium smegmatis

Share to Ultraviolet Rays

Share to Uracil-DNA Glycosidase

Source

Identifiers

PMID: 18757811
DOI: 10.1099/mic.0.2008/019638-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Important role of the nucleotide excision repair pathway in Mycobacterium smegmatis in conferring protection against commonly encountered DNA-damaging agents.PMID 18757811Read ↗

Characterization of the mycobacterial NER system reveals novel functions of the uvrD1 helicase.Semantic proximity Read ↗

Distinct mechanisms of DNA repair in mycobacteria and their implications in attenuation of the pathogen growth.Semantic proximity Read ↗

Base excision and nucleotide excision repair pathways in mycobacteria.Semantic proximity Read ↗

A distinct role of formamidopyrimidine DNA glycosylase (MutM) in down-regulation of accumulation of G, C mutations and protection against oxidative stress in mycobacteria.Semantic proximity Read ↗

The contribution of Nth and Nei DNA glycosylases to mutagenesis in Mycobacterium smegmatis.Semantic proximity Read ↗

Synergistic effects of UdgB and Ung in mutation prevention and protection against commonly encountered DNA damaging agents in Mycobacterium smegmatis.Semantic proximity Read ↗

A combinatorial role for MutY and Fpg DNA glycosylases in mutation avoidance in Mycobacterium smegmatis.Semantic proximity Read ↗

Apurinic/apyrimidinic endonucleases of Mycobacterium tuberculosis protect against DNA damage but are dispensable for the growth of the pathogen in guinea pigs.Semantic proximity Read ↗

DNA repair systems and the pathogenesis of <i>Mycobacterium tuberculosis</i>: varying activities at different stages of infectionSemantic proximity Read ↗

Role for nucleotide excision repair in virulence of Mycobacterium tuberculosis.Semantic proximity Read ↗

The biological and structural characterization of Mycobacterium tuberculosis UvrA provides novel insights into its mechanism of action.Semantic proximity Read ↗

Characterization of a Mycobacterium smegmatis uvrA mutant impaired in dormancy induced by hypoxia and low carbon concentration.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.