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Article

The C2 domain protein Cts1 functions in the calcineurin signaling circuit during high-temperature stress responses in Cryptococcus neoformans.

Eukaryotic cell - 1 Dec 2011

Aboobakar Eanas F, Wang Xuying, Heitman Joseph, Kozubowski Lukasz

Abstract excerpt

Calcineurin is a conserved calcium/calmodulin-dependent serine/threonine-specific protein phosphatase that acts in cell stress responses. Calcineurin is essential for growth at 37°C and for virulence of the human fungal pathogen Cryptococcus neoformans, but its substrates remain unknown. The C2 domain-containing, phospholipid-binding protein Cts1 was previously identified as a multicopy suppressor of a...

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Identifiers

PMID: 22002655
DOI: 10.1128/EC.05148-11
PMCID: PMC3232716

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The C2 domain protein Cts1 functions in the calcineurin signaling circuit during high-temperature stress responses in Cryptococcus neoformans.PMID 22002655Read ↗

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Calcineurin controls the cytokinesis machinery during thermal stress in <i>Cryptococcus deneoformans</i>Semantic proximity Read ↗

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Thermoregulation network governing virulence of a critical human fungal pathogenSemantic proximity Read ↗

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Dissecting the Roles of the Calcineurin Pathway in Unisexual Reproduction, Stress Responses, and Virulence in Cryptococcus deneoformans.Semantic proximity Read ↗

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