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Article

Dissecting the Roles of the Calcineurin Pathway in Unisexual Reproduction, Stress Responses, and Virulence in Cryptococcus deneoformans.

Genetics - 1 Feb 2018

Fu Ci, Donadio Nicholas, Cardenas Maria E, Heitman Joseph

Abstract excerpt

The Ca2+/calmodulin-dependent protein phosphatase calcineurin orchestrates sexual reproduction, stress responses, and virulence via branched downstream pathways in the opportunistic human fungal pathogen Cryptococcus neoformans The calcineurin-binding protein Cbp1, the calcineurin temperature suppressor Cts1, the calcineurin-responsive zinc finger transcription factor Crz1, and the calcineurin targets Pbp1, Tif3,...

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Identifiers

PMID: 29233811
DOI: 10.1534/genetics.117.300422
PMCID: PMC5788528

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Dissecting the Roles of the Calcineurin Pathway in Unisexual Reproduction, Stress Responses, and Virulence in Cryptococcus deneoformans.PMID 29233811Read ↗

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Had1 Is Required for Cell Wall Integrity and Fungal Virulence in Cryptococcus neoformans.Semantic proximity Read ↗

Calcineurin controls the cytokinesis machinery during thermal stress in <i>Cryptococcus deneoformans</i>Semantic proximity Read ↗

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The enigmatic role of fungal annexins: the case of <i>Cryptococcus neoformans</i>Semantic proximity Read ↗

Identification and characterization of a highly conserved calcineurin binding protein, CBP1/calcipressin, in Cryptococcus neoformans.Semantic proximity Read ↗

The Crz1/Sp1 Transcription Factor of Cryptococcus neoformans Is Activated by Calcineurin and Regulates Cell Wall IntegritySemantic proximity Read ↗

The C2 domain protein Cts1 functions in the calcineurin signaling circuit during high-temperature stress responses in Cryptococcus neoformans.Semantic proximity Read ↗

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