Article
Had1 Is Required for Cell Wall Integrity and Fungal Virulence in Cryptococcus neoformans.
G3 (Bethesda, Md.) - 2 Feb 2018
Jung Won-Hee, Son Ye-Eun, Oh Sang-Hun, Fu Ci, Kim Hye Shin, Kwak Jin-Hwan, Cardenas Maria E, Heitman Joseph, Park Hee-Soo
Abstract excerpt
Calcineurin modulates environmental stress survival and virulence of the human fungal pathogen Cryptococcus neoformans Previously, we identified 44 putative calcineurin substrates, and proposed that the calcineurin pathway is branched to regulate targets including Crz1, Pbp1, and Puf4 in C. neoformans In this study, we characterized Had1, which is one of the putative calcineurin substrates belonging to the...
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