Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Calcium- and calcineurin-independent roles for calmodulin in Cryptococcus neoformans morphogenesis and high-temperature growth.

Eukaryotic cell - 1 Jun 2005

Kraus Peter R, Nichols Connie B, Heitman Joseph

Abstract excerpt

The function of calcium as a signaling molecule is conserved in eukaryotes from fungi to humans. Previous studies have identified the calcium-activated phosphatase calcineurin as a critical factor in governing growth of the human pathogenic fungus Cryptococcus neoformans at mammalian body temperature. Here, we employed insertional mutagenesis to identify new genes required for growth at 37 degrees C. One...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calcineurin
Share to Calcium
Share to Calmodulin

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cryptococcus neoformans

Share to Genes, Fungal

Share to Hot Temperature

Share to Mutagenesis, Insertional

Share to Tacrolimus

Source

Open in PubMed Open full text

Identifiers

PMID: 15947200
DOI: 10.1128/EC.4.6.1079-1087.2005
PMCID: PMC1151996

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Calcium- and calcineurin-independent roles for calmodulin in Cryptococcus neoformans morphogenesis and high-temperature growth.PMID 15947200Read ↗

Elucidation of the calcineurin-Crz1 stress response transcriptional network in the human fungal pathogen Cryptococcus neoformans.Semantic proximity Read ↗

The C2 domain protein Cts1 functions in the calcineurin signaling circuit during high-temperature stress responses in Cryptococcus neoformans.Semantic proximity Read ↗

Identification and characterization of a highly conserved calcineurin binding protein, CBP1/calcipressin, in Cryptococcus neoformans.Semantic proximity Read ↗

The Crz1/Sp1 Transcription Factor of Cryptococcus neoformans Is Activated by Calcineurin and Regulates Cell Wall IntegritySemantic proximity Read ↗

Calcineurin is essential for Candida albicans survival in serum and virulence.Semantic proximity Read ↗

The calcineurin pathway regulates extreme thermotolerance, cell membrane and wall integrity, antifungal resistance, and virulence in Candida aurisSemantic proximity Read ↗

Calcineurin controls the cytokinesis machinery during thermal stress in <i>Cryptococcus deneoformans</i>Semantic proximity Read ↗

Functional Characterization of an Aspergillus fumigatus Calcium Transporter (PmcA) that Is Essential for Fungal InfectionSemantic proximity Read ↗

Thermoregulation network governing virulence of a critical human fungal pathogenSemantic proximity Read ↗

Convergent Evolution of Calcineurin Pathway Roles in Thermotolerance and Virulence in<i>Candida glabrata</i>Semantic proximity Read ↗

Functional characterization of the Aspergillus fumigatus calcineurin.Semantic proximity Read ↗

Had1 Is Required for Cell Wall Integrity and Fungal Virulence in Cryptococcus neoformans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.