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Increased expression of histone deacetylases 2 in temporal lobe epilepsy: A study of epileptic patients and rat models

10 Oct 2011

Abstract excerpt

Histone deacetylases 2 (HDAC2) is expressed in the central nervous system; it has multiple functions in neural plasticity. However, we do not know if HDAC2 is also involved in the pathology of epilepsy. Here we report that HDAC2 was expressed in the brain tissues of both control and temporal lobe epilepsy (TLE) patients. Results from immunofluorescence and immunohistochemistry showed that HDAC2 was primarily...

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PMID: 21987499
DOI: 10.1002/syn.20995

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