Article
Amygdala gene expression of NMDA and GABA(A) receptors in patients with mesial temporal lobe epilepsy.
Hippocampus - 1 Jan 2012
de Moura José Carlos, Tirapelli Daniela P C, Neder Luciano, Saggioro Fabiano P, Sakamoto Americo Ceiki, Velasco Tonicarlo R, Panepucci Rodrigo A, Leite João Pereira, Assirati Júnior João Alberto, Colli Benedicto Oscar, Carlotti Júnior Carlos Gilberto
Abstract excerpt
Temporal lobe epilepsy (TLE) is the most common form of partial epilepsy and affects 40% of the patients. Seizures arising from the mesial temporal lobe structures (i.e., amygdala and hippocampus) are common, whereas neocortical seizures are rare. In recent years, many studies aimed to identify the pattern of gene expression of neurotransmitters involved in molecular mechanisms of epilepsy. We used real-time PCR...
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