Article

Rho-associated Protein Kinase 2 Confers Epileptogenesis through the Activation of Astroglial Stat3 Pathway

2020-12-01

Abstract excerpt

Patients with temporal lobe epilepsy (TLE) are prone to tolerance to antiepileptic drugs. Based on the perspective of molecular targets for drug resistance, it is necessary to explore effective drug resistant genes and signaling pathways for the treatment of TLE. We performed gene expression profiles in hippocampus of patients with drug-resistant TLE and identified ROCK2 as one of the 20 most significantly increas...

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Literature Corpus work: 6d05dcea-3f6e-56b9-94e7-6ec632457a9e
DOI: 10.21203/rs.3.rs-115889/v1

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