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Article

Evaluation of heterogeneity in the association between congenital heart defects and variants of folate metabolism genes: conotruncal and left-sided cardiac defects.

Birth defects research. Part A, Clinical and molecular teratology - 1 Oct 2011

Long Jin, Lupo Philip J, Goldmuntz Elizabeth, Mitchell Laura E

Abstract excerpt

BACKGROUND: Genetic variation in the folate metabolic pathway may influence the risk of congenital heart defects. This study was undertaken to assess the associations between the inherited and maternal genotypes for variants in folate-related genes and the risk of a composite heart phenotype that included two component phenotypes: conotruncal heart defects (CTDs) and left-sided cardiac lesions (LSLs). METHODS:...

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Identifiers

PMID: 21987465
DOI: 10.1002/bdra.22849
PMCID: PMC3257803

Genes

MTR

Variants

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