Article
Efficient two-stage genome-wide association designs based on false positive report probabilities.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2006
Kraft Peter
Abstract excerpt
Despite recent advances, very-high-throughput (VHT) technologies capable of genotyping hundreds of thousands of SNPs in individual samples remain prohibitively expensive for the large studies necessary to screen substantial sections of the genome for variants with modest effects on disease risk. This paper presents a two-stage strategy, where a portion of available samples are genotyped with VHT technology, and a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
