Article
Ranks of genuine associations in whole-genome scans.
Genetics - 1 Oct 2005
Zaykin Dmitri V, Zhivotovsky Lev A
Abstract excerpt
With the recent advances in high-throughput genotyping techniques, it is now possible to perform whole-genome association studies to fine map causal polymorphisms underlying important traits that influence susceptibility to human diseases and efficacy of drugs. Once a genome scan is completed the results can be sorted by the association statistic value. What is the probability that true positives will be...
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