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Article

Striking conservation of TFIID in Schizosaccharomyces pombe and Saccharomyces cerevisiae.

Nature - 19 Jul 1990

Fikes J D, Becker D M, Winston F, Guarente L

Abstract excerpt

Eukaryotic promoters contain binding sites for basic transcription factors and gene-specific activator proteins. The transcription factors interact at the TATA box, which lies close to the position of transcription initiation. Activators typically bind to distant sites that can lie kilobases away from the initiation site. The factor TFIID binds specifically to the TATA box to initiate an ordered pathway of...

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PMID: 2197558
DOI: 10.1038/346291a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Striking conservation of TFIID in Schizosaccharomyces pombe and Saccharomyces cerevisiae.PMID 2197558Read ↗

Molecular genetic elucidation of the tripartite structure of the Schizosaccharomyces pombe 72 kDa TFIID subunit which contains a WD40 structural motif.Semantic proximity Read ↗

Analysis of structure-function relationships of yeast TATA box binding factor TFIID.Semantic proximity Read ↗

Isolation and cloning of four subunits of a fission yeast TFIIIC complex that includes an ortholog of the human regulatory protein TFIIICbeta.Semantic proximity Read ↗

Characterization of the Schizosaccharomyces pombe Spt5-Spt4 complex.Semantic proximity Read ↗

SPT3 interacts with TFIID to allow normal transcription in Saccharomyces cerevisiae.Semantic proximity Read ↗

Histone H3K4 and K36 methylation, Chd1 and Rpd3S oppose the functions of Saccharomyces cerevisiae Spt4-Spt5 in transcription.Semantic proximity Read ↗

Yeast and human TATA-binding proteins have nearly identical DNA sequence requirements for transcription in vitro.Semantic proximity Read ↗

Biochemical and genetic characterization of a yeast TFIID mutant that alters transcription in vivo and DNA binding in vitro.Semantic proximity Read ↗

SPT20/ADA5 encodes a novel protein functionally related to the TATA-binding protein and important for transcription in Saccharomyces cerevisiae.Semantic proximity Read ↗

Molecular genetic dissection of TAF25, an essential yeast gene encoding a subunit shared by TFIID and SAGA multiprotein transcription factors.Semantic proximity Read ↗

Analysis of the splicing machinery in fission yeast: a comparison with budding yeast and mammals.Semantic proximity Read ↗

Two Novel <i>Drosophila</i> TAF<sub>II</sub>s Have Homology with Human TAF<sub>II</sub>30 and Are Differentially Regulated during DevelopmentSemantic proximity Read ↗

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