Article
Histone H3K4 and K36 methylation, Chd1 and Rpd3S oppose the functions of Saccharomyces cerevisiae Spt4-Spt5 in transcription.
Genetics - 1 Feb 2010
Quan Tiffani Kiyoko, Hartzog Grant Ashley
Abstract excerpt
Spt4-Spt5, a general transcription elongation factor for RNA polymerase II, also has roles in chromatin regulation. However, the relationships between these functions are not clear. Previously, we isolated suppressors of a Saccharomyces cerevisiae spt5 mutation in genes encoding members of the Pa...
Topics
- Acetylation
- Chromatin
- Chromosomal Proteins, Non-Histone
- Conserved Sequence
- DNA-Binding Proteins
- Histone Deacetylases
- Histones
- Kinetics
- Lysine
- Methylation
- Mutation
- Nuclear Proteins
- Nucleosomes
- Protein Structure, Tertiary
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Transcription, Genetic
- Transcriptional Elongation Factors